Devices

Wet-spun PEDOT:PSS fibre about 15 micrometers across with PDMS insulation and a magnetic susceptibility of -9.23 ppm matched to brain tissue, giving little to no artifact at 11.7 T. 11.9 kOhm at 1 kHz for a 20 micrometer fibre, charge injection limit 14.3 mC/cm2, used to stimulate and record in rats during multimodal MRI. Fudan University (National Science Review 2026).

Catalog specification sheet - Intracortical

Fudan MRI-compatible PEDOT:PSS fiber electrode (MFE)

Record ID
BTSD-ACAD-0109
Reviewed
2026-10-09
Interface
intracortical
Evidence stage
preclinical

Independent, source-linked catalog sheet. Not a manufacturer-issued datasheet, regulatory decision or instructions for clinical use. Human evidence does not establish approval. Source-specific restrictions, conflicts and missing specifications are retained below.

Fudan MRI-compatible PEDOT:PSS fiber electrode (MFE)

A soft conductive-polymer fibre electrode that can sit in the brain during ultra-high-field MRI without distorting the images, so electrical stimulation can be mapped across the whole brain while it is delivered. From Fudan University’s Institute of Fiber Materials and Devices, the Institute of Science and Technology for Brain-Inspired Intelligence and the Neuromodulation and Brain-machine-interface Center; authors include Li Wenjun, Li Xiao, Peng Huisheng and Sun Xiaoyu. Paper: “MRI-compatible soft fiber bioelectronics for multimodal assessment of electrical neural stimulation on whole-brain activation”, National Science Review 2026, DOI 10.1093/nsr/nwag325 (open access, PMC13358296).

Identity

FieldValue and source scope
DeviceMRI-compatible fibre neural electrode, MFE [1]
OriginFudan University, Shanghai [1]
SpeciesRat, including an autism spectrum disorder model and wild-type controls [1]
Regulatory statusResearch device [1]

Geometry and architecture

FieldValue and source scope
FormSingle conductive fibre, about 15 um in diameter; fibres of about 20, 40 and 80 um were also tested for artifacts [1]
Device formatFour-channel MRI-compatible neural devices with custom flexible printed circuit boards [1]
InsulationPDMS coating, about 3 um thick in the artifact comparison [1]
Exposed site length

Materials and fabrication

FieldValue and source scope
ConductorPEDOT:PSS, wet-spun with DMSO in the suspension and coagulation baths to drive PEDOT/PSS phase separation and remove excess insulating PSS; infiltrated with glycerol to add disorder and flexibility [1]
Magnetic propertyMagnetic susceptibility -9.23 ppm, close to brain tissue; the authors attribute this to the spinning process [1]
ImplantationMinimally invasive, tungsten-wire-assisted; tissue damage under 100 um around the site [1]

Performance envelope

FieldValue and source scope
MRI artifactLittle to no artifact at 11.7 T; compared with PtIr electrodes of the same diameter in agarose and rat brain (n = 4 per size), with no detectable B0 distortion around MFEs of any tested diameter [1]
Impedance11.9 kOhm at 1 kHz for a 20 um fibre, against 148 kOhm for PtIr of the same diameter [1]
Charge injectionCIL 14.3 mC/cm2, against 0.121 mC/cm2 for PtIr; a 12.5 mC/cm2 value is also stated for another electrode in the same comparison [1]
Application resultStimulation synchronized with LFP and multimodal MRI (fMRI, DWI, MRS) at 11.7 T; frequency-dependent whole-brain responses to medial prefrontal cortex stimulation in ASD and wild-type rats, with high-frequency stimulation regulating some regions in ASD rats [1]

Limits

Rat study. Chronic implantation was assessed by immune-cell distribution; duration and yield figures were not extracted here. Modulus and site length are blank.

References

  1. Li W, Li X, Yang H et al., MRI-compatible soft fiber bioelectronics for multimodal assessment of electrical neural stimulation on whole-brain activation, National Science Review (2026), DOI 10.1093/nsr/nwag325; full text PMC13358296.