Probe with a tip about 100 nm across and a sensing region exposed over about 40 nm, so only the tip site sits inside one neuron. Records intracellular action potentials up to about 70 mV and synaptic currents in live mouse. Liu Jingquan's group at Shanghai Jiao Tong University (IEEE MEMS 2026 award paper).
Catalog specification sheet - Intracortical
SJTU implantable nanoscale neural probe (INNP) for in vivo intracellular recording
Independent, source-linked catalog sheet. Not a manufacturer-issued datasheet, regulatory decision or instructions for clinical use. Human evidence does not establish approval. Source-specific restrictions, conflicts and missing specifications are retained below.
SJTU implantable nanoscale neural probe (INNP)
A penetrating probe small enough to enter a single neuron in the living brain and record from inside it, rather than from outside as microelectrodes do. From Liu Jingquan’s team at the National Key Laboratory of Micro/Nano Fabrication Technology, Shanghai Jiao Tong University; first author Du Zhiyuan. Paper: “Implantable Nanoscale Neural Probe for Single-Neuron Intracellular Electrophysiological Analysis In Vivo”, IEEE MEMS 2026 (Salzburg, 25 to 29 January 2026), outstanding student paper award. The source is SJTU’s Chinese news release of 6 February 2026. The conference paper was not read, so materials, fabrication steps and impedance are blank.
Identity
Field
Value and source scope
Device
Implantable nanoscale neural probe, INNP [1]
Origin
Shanghai Jiao Tong University, School of Integrated Circuits, Liu Jingquan (corresponding), Du Zhiyuan (first author) [1]
Species
Mouse [1]
Regulatory status
Research device [1]
Geometry and architecture
Field
Value and source scope
Tip diameter
About 100 nm [1]
Exposed sensing length
As low as about 40 nm, so only the tip site lies inside the neuron and the non-sensing shaft does not pick up extracellular signals or ambient noise [1]
Channels
Materials and fabrication
Field
Value and source scope
Nanotip processing
Described as nano-tip micro-fabrication; atmospheric-pressure plasma jet micro-nano processing is the first author’s stated research area [1]
Materials, insulation, steps
Performance envelope
Field
Value and source scope
Intracellular signals
Action potentials up to about 70 mV and postsynaptic currents from hundreds to thousands of pA, recorded in vivo in mouse [1]
Multimodal
Records electrophysiology and several biochemical markers at once [1]
Pain-stimulus result
Pain stimulation increased the amplitude of negative postsynaptic current spikes, narrowed their half width and produced clear positive spikes [1]
Stability and safety
Described as electrochemically stable, biocompatible and minimally damaging; no numbers given [1]
Limits
Conference result reported by the university. Recording duration, yield and neuron counts are not stated. The same group has related probes in cell culture and a nanotube optical-electrical probe (see sheet 206).