CORTEX / INTEGRATED EXPERIMENT

Neural Interface Laboratory

One shank. Twelve human neurons. Matched experiments in stimulation and recording.

Model & evidence ↗

Membrane activity

Membrane voltage−100 mV+40 mVSame voltage scale for every cell
0.0 ms
Cell 1 soma events

Slow-motion loop of one computed 260 ms window. Colors show each compartment’s solved voltage; replay does not generate new spikes. Reduced-motion preferences pause automatic playback.

Loading the computed 12-cell recording…

Inspect a cell

Selected Vm — mV
Somatic events— / window
Somatic drive— nA
Specimen—

Select a soma, dendrite or axon compartment to follow its solved membrane voltage. Paired traces use identical compartment indices and voltage axes.

Surface recording

0.0 ms—Raw potential · reference at infinity

The neural trace is a known contribution from the solver, not a signal recovered from stimulation artifact. Direct artifact can be orders of magnitude larger. Shared gain is fixed across contacts and both conditions for the chosen signal and source selection. Raw samples remain in exports. No electrode impedance, noise, amplifier saturation or spike sorting is modeled.

Somatic spike raster

12 independent cells

Ticks require a −25 mV upward crossing, a peak ≥ 0 mV and return below −40 mV. These are known simulated soma events, not spikes detected or sorted from the contact trace. Marks above each plot show stimulus times; coincidence alone does not establish causation.

Cell 1 event times · 0 entries
ConditionEventTime · msReplay
No complete soma events in the selected cell’s window.

What this experiment establishes

All cells run the original human active membrane models. Stimulation and recording share one coupled finite surface-contact solution. The visible shank uses a planar insulating backing approximation: its tip, sides and back do not yet shape the field. Matched comparisons isolate an input within this model; they do not establish an optimal implant or validate a new configuration against native NEURON.

Read equations, provenance and validation scope ↗
Original Cortex Laboratory